Research output per year
Research output per year
Personal profile
Overview
Biography
Dominik did his undergraduate degree (Dipl.-Ing.(Univ.) equivalent MSc) in Medical Biotechnology at the Technical University of Berlin, Germany. Then Dominik went on to undertake his doctoral studies (Dr. rer.nat. equivalent PhD) at the Research Center Borstel, Germany, associated with the University of Lübeck, Germany, characterising the impact and importance of the Interleukin 12 family of cytokines on the innate immune response to Mycobacterium tuberculosis infection. In late 2007 he trsnlocated to the United Kingdom joining the laboratory of Prof. Judith Allen at the University of Edinburgh where he studied the biology of macrophages in helminth infections. In early 2016 the laboratory relocated to Manchester where he was awarded a Faculty Stepping Stone Fellowship to start his independent career. His research focussed on the role of differernt macrophage subsets in the progression and development of intra-abdominal fibrotic conditions like post surgical adhesions and peritoneal dialysis associated Encapsulating peritoneal sclerosis. Since 2024 he is now a teaching-focussed Lecturer in Medical Education helping early stage students in Medicine, Dentistry and Pharmacy to a running start to their careers.
Teaching Activity
- International Foundation Programme in Medicine, Dentistry and Pharmacy (IFP):
EBL tutor
TBL lead
Academic Advisor
- MSc Clinical Immunology:
Unit Lead - Research Project Proposal
Project supervisor - MBChB:
Y1 & Y2 PEP Supervisor
APEP Supervisor
Academic Advisor
CCA assessment - BDS Dentistry:
EBL tutor
Academic Advisor
Social Responsibility
- Manchester Access Programme (MAP):
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Fellow of The Higher Education Academy, Advance HE
Award Date: 19 Jul 2019
Doctor rerum naturalium, The impact of IL-27- and IL-23-mediated mechanisms on inflammatory immune reactions under special consideration of the infection with Mycobacterium tuberculosis, Universitat zu Lubeck
1 May 2004 → 31 Oct 2007
Award Date: 28 Aug 2007
Master in Science, Technische Universitat Berlin
Award Date: 5 Sept 2003
Areas of expertise
- QR180 Immunology
- Macrophage
- helminth infection
- innate immune system
- co-infection
- peritoneal fibrosis
Keywords
- Immunology
- Infection
- Inflammation
- Macrophage
- TBL
- EBL
Fingerprint
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity
Finlay, C. M., Parkinson, J. E., Zhang, L., Chan, B. H. K., Ajendra, J., Chenery, A., Morrison, A., Kaymak, I., Houlder, E. L., Murtuza Baker, S., Dickie, B. R., Boon, L., Konkel, J. E., Hepworth, M. R., MacDonald, A. S., Randolph, G. J., Rückerl, D. & Allen, J. E., 15 Mar 2023, In: Immunity.Research output: Contribution to journal › Article › peer-review
Open Access -
CD11c identifies microbiota and EGR2-dependent MHCII+ serous cavity macrophages with sexually dimorphic fate in mice
Bain, C. C., Louwe, P. A., Steers, N. J., Bravo-Blas, A., Hegarty, L. M., Pridans, C., Milling, S. W. F., MacDonald, A. S., Rückerl, D. & Jenkins, S. J., 24 May 2022, In: European journal of immunology.Research output: Contribution to journal › Article › peer-review
Open Access -
High-Dose Mycobacterium tuberculosis H37rv Infection in IL-17A- and IL-17A/F-Deficient Mice
Ritter, K., Behrends, J., Ruckerl, D., Hölscher, A., Volz, J., Prinz, I. & Hölscher, C., 14 Sept 2022, In: Cells. 11, 18, 2875.Research output: Contribution to journal › Article › peer-review
Open Access -
Monocyte-derived peritoneal macrophages protect C57BL/6 mice against surgery-induced adhesions
Sahputra, R., Dejyong, K., Woolf, A. S., Mack, M., Allen, J., Rückerl, D. & Herrick, S., 13 Sept 2022, (Accepted/In press) In: Frontiers in Immunology.Research output: Contribution to journal › Article › peer-review
Open Access -
Post-transcriptional regulatory feedback encodes JAK-STAT signal memory of interferon stimulation
Kalliara, E., Kardyńska, M., Bagnall, J., Spiller, D. G., Muller, W., Ruckerl, D., Biswas, S. K., Śmieja, J. & Paszek, P., 27 Sept 2022, In: Frontiers in Immunology. 13, 947213, 947213.Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 1 Finished
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Defining Functional Impacts of Macrophages in the Formation of Surgical Adhesions.
Herrick, S. (PI), Allen, J. (CoI), Ruckerl, D. (CoI) & Woolf, A. (CoI)
1/09/19 → 20/07/23
Project: Research
Activities
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2nd International Summer School in Medicine
Ruckerl, D. (Co-Organiser) & England, H. (Organiser)
2025Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Teaching
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1st International Summer School in Medicine
Ruckerl, D. (Co-Organiser) & England, H. (Organiser)
2024 → …Activity: Participating in or organising event(s) › Organising a conference, workshop, exhibition, performance, inquiry, course etc › Teaching
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Macrophage heterogeneity and activation plasticity: Two sides of two coins
Ruckerl, D. (Invited speaker)
19 Dec 2017Activity: Talk or presentation › Invited talk › Research
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British Society for Immunology Congress 2017
Ruckerl, D. (Poster presenter)
4 Dec 2017 → 7 Dec 2017Activity: Participating in or organising event(s) › Participating in a conference, workshop, exhibition, performance, inquiry, course etc › Research
Datasets
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Ncounter Fibrosis panel gene expression analysis
Ruckerl, D. (Creator), University of Manchester, 26 May 2021
DOI: 10.48420/14635917.v1, https://figshare.manchester.ac.uk/articles/dataset/Ncounter_Fibrosis_panel_gene_expression_analysis/14635917/1
Dataset
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The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p
Czimmerer, Z. (Contributor), Varga, T. (Contributor), Kiss, M. (Contributor), Vázquez, C. O. (Contributor), Doan-Xuan, Q. M. (Contributor), Ruckerl, D. (Contributor), Tattikota, S. G. (Contributor), Yan, X. (Contributor), Nagy, Z. S. (Contributor), Daniel, B. (Contributor), Poliska, S. (Contributor), Horvath, A. (Contributor), Nagy, Z. S. (Contributor), Varallyay, E. (Contributor), Poy, M. N. (Contributor), Allen, J. (Contributor), Bacso, Z. (Contributor), Abreu-Goodger, C. (Contributor) & Nagy, Z. S. (Contributor), figshare , 31 May 2016
DOI: 10.6084/m9.figshare.c.3643313.v1, https://figshare.com/collections/The_IL-4_STAT6_signaling_axis_establishes_a_conserved_microRNA_signature_in_human_and_mouse_macrophages_regulating_cell_survival_via_miR-342-3p/3643313/1
Dataset