Research output per year
Research output per year
Personal profile
Teaching
BIOL31582 Cardiovascular Systems
Overview
Research Fellow at the University of Manchester, Division of Cardiovascular Sciences
Biography
Dr Samantha Borland obtained her Bachelor's degree in Pharmacology & Physiology at the University of Manchester. She completed her PhD in 2015 in Cardiovascular Medicine, entitled "Regulation of vascular calcification by syndecan 4". Throughout her PhD, Dr Borland has presented at numerous national and international conferences, and won best poster prizes at the British Society of Cardiovascular Research/British Atherosclerosis Society Meeting and Gordon Proteoglycan Research Conference. Her current research interests are in the regulation of vascular calcification by PKCα and TGFβ signalling.
Qualifications
Sept 2011 - Sept 2015: PhD in Cardiovascular Medicine
Sept 2007 - July 2011: BSc Pharmacology & Physiology (w/ Industrial Experience) with Honours
Memberships of committees and professional bodies
Professional memberships:
Fellow of Higher Education Academy
Society memberships:
British Atherosclerosis Society
North American Vascular Biology Organization
British Society for Cardiovascular Research
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Industrial Placement student, Safety Assessment, AstraZeneca
1 Sept 2009 → 1 Sept 2010
Areas of expertise
- QP Physiology
- Vascular biology
Keywords
- Vascular calcification
- Vascular smooth muscle cell
- PKCα
- Syndecan 4
- Atherosclerosis
- Chronic kidney disease
- Micro computed tomography
Fingerprint
Dive into the research topics where Samantha Borland is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Research output
- 8 Article
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Regulation of vascular smooth muscle cell calcification by syndecan-4/FGF-2/PKCα signaling and cross-talk with TGFβ
Borland, S., Morris, T., Borland, S. C., Morgan, M. R., Francis, S. E., Merry, C. L. R. & Canfield, A., Nov 2017, In: Cardiovascular research. 113, p. 1639-1652 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
X-ray micro computed tomography: an emerging technology to analyze vascular calcification in animal models
Borland, S., Behnsen, J., Ashton, N., Francis, S. E., Brennan, K., Sherratt, M., Withers, P. & Canfield, A., 19 Jun 2020, (Accepted/In press) In: International Journal of Molecular Sciences.Research output: Contribution to journal › Article › peer-review
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Loss of PKCα increases arterial medial calcification in a uremic mouse model of chronic kidney disease
Borland, S. J., Facchi, C., Behnsen, J., Adamson, A., Humphreys, N. E., Withers, P. J., Sherratt, M. J., Francis, S. E., Brennan, K., Ashton, N. & Canfield, A. E., 21 May 2020, In: bioRxiv.Research output: Contribution to journal › Article › peer-review
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FTI-277 inhibits smooth muscle cell calcification by up-regulating PI3K/Akt signaling and inhibiting apoptosis
Ponnusamy, A., Sinha, S., Hyde, G. D., Borland, S., Taylor, R., Pond, E., Eyre, H., Inkson, C., Gilmore, A., Ashton, N., Kalra, P. & Canfield, A., 2018, In: PlosOne.Research output: Contribution to journal › Article › peer-review
Open Access -
Sphingosine 1-phosphate activation of ERM contributes to vascular calcification
Morris, T., Borland, S., Clarke, C. J., Wilson, C., Hannun, Y. A., Ohanian, V., Canfield, A. & Ohanian, J., Jan 2018, In: Journal of Lipid Research. 59, p. 69-78 DOI https://doi.org/10.1194/jlr.M079731.Research output: Contribution to journal › Article › peer-review
Open AccessFile183 Downloads (Pure)
Projects
- 2 Finished
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PKC/TGF- SIGNALLING AXIS: A NOVEL THERAPEUTIC TARGET FOR ARTERIAL MEDIAL CALCIFICATION
Borland, S. (PI), Canfield, A. (CoI), Brennan, K. (CoI), Ashton, N. (CoI) & Sherratt, M. (CoI)
1/02/21 → 31/01/24
Project: Research
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PKCa: A Potential New Therapeutic Target for Cardiovascular Disease.
Brennan, K. (PI), Ashton, N. (CoI), Borland, S. (CoI), Canfield, A. (CoI) & Sherratt, M. (CoI)
1/05/18 → 31/10/20
Project: Research
Prizes
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Best oral presentation prize: Developmental Biology & Cell-Matrix Biology Joint 3rd Year PhD Symposium, University of Manchester, UK
Borland, S. (Recipient), 2015
Prize: Prize (including medals and awards)
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Best oral presentation prize: Northern Vascular Biology Forum, Sheffield Hallam University, UK
Borland, S. (Recipient), 2019
Prize: Prize (including medals and awards)
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Best poster prize: BSCR/BAS Meeting, Manchester, UK.
Borland, S. (Recipient), 2015
Prize: Prize (including medals and awards)
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Best poster prize: Gordon Proteoglycan Research Conference, Andover, NH
Borland, S. (Recipient), 2014
Prize: Prize (including medals and awards)
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Best poster prize: Manchester Academic and Health Sciences Conference, Manchester, UK
Borland, S. (Recipient), 2013
Prize: Prize (including medals and awards)
Activities
- 1 Membership of professional association
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The Higher Education Academy (External organisation)
Borland, S. (Academic expert member)
2021Activity: Membership › Membership of professional association › Research
Thesis
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REGULATION OF VASCULAR CALCIFICATION BY SYNDECAN 4
Borland, S. (Author), Canfield, A. (Supervisor) & Merry, C. (Supervisor), 1 Aug 2016Student thesis: Phd
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