Development and translation of a method of clinical utility for LC-MS/MS analysis to detect SARS-CoV-2 antigens from ONP swabs and saliva

N Leigh Anderson; Alistair Bailey; Perdita Barran; Philip Brownbridge; Kathleen Cain; Rachel Carling; Rainer Cramer; R Neil Dalton; Matthew E Daly; Kayleigh Davis; Ivan Doykov; Maria Emilia Dueñas; Edward Emmott; Claire E Eyers; Akshada Gajbhiye; Bethany Geary; Pankaj Gupta; Jenny Hällqvist; Evita Hartmane; Simon Heales; Tiaan Heunis; Wendy Heywood; Katherine A Hollywood; Rosalind E Jenkins; Donald JL Jones; Brian Keevil; Henriette Krenkel; Dan Lane; Catherine S Lane; Sophie Lellman; Ellen N Liggett; Xiaoli Meng; Clare Mills; Kevin Mills; Atakan A Nalbant; Leong L Ng; Benjamin Nicholas; Dan Noels; Terry W Pearson; Andrew Pitt; Matthew E Pope; Andrew Porter; George W Preston; Morteza Razavi; Andrew Shapanis; Frances R Sidgwick; Raj Singh; Paul Skipp; Reynard Speiss; Justyna Spiewak; Anna L Tierney; Drupad Trivedi; Matthias Trost; Richard D Unwin; Luke Wainwright; Caitlin Walton-Doyle; Anthony D Whetton; Sandra Wilks; Richard Yip

doi:10.26434/chemrxiv-2024-4t52c

Development and translation of a method of clinical utility for LC-MS/MS analysis to detect SARS-CoV-2 antigens from ONP swabs and saliva

N Leigh Anderson, Alistair Bailey, Perdita Barran, Philip Brownbridge, Kathleen Cain, Rachel Carling, Rainer Cramer, R Neil Dalton, Matthew E Daly, Kayleigh Davis, Ivan Doykov, Maria Emilia Dueñas, Edward Emmott, Claire E Eyers, Akshada Gajbhiye, Bethany Geary, Pankaj Gupta, Jenny Hällqvist, Evita Hartmane, Simon HealesTiaan Heunis, Wendy Heywood, Katherine A Hollywood, Rosalind E Jenkins, Donald JL Jones, Brian Keevil, Henriette Krenkel, Dan Lane, Catherine S Lane, Sophie Lellman, Ellen N Liggett, Xiaoli Meng, Clare Mills, Kevin Mills, Atakan A Nalbant, Leong L Ng, Benjamin Nicholas, Dan Noels, Terry W Pearson, Andrew Pitt, Matthew E Pope, Andrew Porter, George W Preston, Morteza Razavi, Andrew Shapanis, Frances R Sidgwick, Raj Singh, Paul Skipp, Reynard Speiss, Justyna Spiewak, Anna L Tierney, Drupad Trivedi, Matthias Trost, Richard D Unwin, Luke Wainwright, Caitlin Walton-Doyle, Anthony D Whetton, Sandra Wilks, Richard Yip

Research output: Preprint/Working paper › Working paper

Original language	English
Publisher	ChemRxiv
DOIs	https://doi.org/10.26434/chemrxiv-2024-4t52c
Publication status	Published - 2 Sept 2024

Keywords

LC-MS
SARS-CoV-2
diagnosis
clinical
proteomics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.26434/chemrxiv-2024-4t52cLicence: CC BY-NC-ND

Cite this

Anderson, N. L., Bailey, A., Barran, P., Brownbridge, P., Cain, K., Carling, R., Cramer, R., Dalton, R. N., Daly, M. E., Davis, K., Doykov, I., Dueñas, M. E., Emmott, E., Eyers, C. E., Gajbhiye, A., Geary, B., Gupta, P., Hällqvist, J., Hartmane, E., ... Yip, R. (2024). Development and translation of a method of clinical utility for LC-MS/MS analysis to detect SARS-CoV-2 antigens from ONP swabs and saliva. ChemRxiv. https://doi.org/10.26434/chemrxiv-2024-4t52c

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author = "Anderson, \{N Leigh\} and Alistair Bailey and Perdita Barran and Philip Brownbridge and Kathleen Cain and Rachel Carling and Rainer Cramer and Dalton, \{R Neil\} and Daly, \{Matthew E\} and Kayleigh Davis and Ivan Doykov and Due{\~n}as, \{Maria Emilia\} and Edward Emmott and Eyers, \{Claire E\} and Akshada Gajbhiye and Bethany Geary and Pankaj Gupta and Jenny H{\"a}llqvist and Evita Hartmane and Simon Heales and Tiaan Heunis and Wendy Heywood and Hollywood, \{Katherine A\} and Jenkins, \{Rosalind E\} and Jones, \{Donald JL\} and Brian Keevil and Henriette Krenkel and Dan Lane and Lane, \{Catherine S\} and Sophie Lellman and Liggett, \{Ellen N\} and Xiaoli Meng and Clare Mills and Kevin Mills and Nalbant, \{Atakan A\} and Ng, \{Leong L\} and Benjamin Nicholas and Dan Noels and Pearson, \{Terry W\} and Andrew Pitt and Pope, \{Matthew E\} and Andrew Porter and Preston, \{George W\} and Morteza Razavi and Andrew Shapanis and Sidgwick, \{Frances R\} and Raj Singh and Paul Skipp and Reynard Speiss and Justyna Spiewak and Tierney, \{Anna L\} and Drupad Trivedi and Matthias Trost and Unwin, \{Richard D\} and Luke Wainwright and Caitlin Walton-Doyle and Whetton, \{Anthony D\} and Sandra Wilks and Richard Yip",

year = "2024",

month = sep,

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Anderson, NL, Bailey, A, Barran, P, Brownbridge, P, Cain, K, Carling, R, Cramer, R, Dalton, RN, Daly, ME, Davis, K, Doykov, I, Dueñas, ME, Emmott, E, Eyers, CE, Gajbhiye, A, Geary, B, Gupta, P, Hällqvist, J, Hartmane, E, Heales, S, Heunis, T, Heywood, W, Hollywood, KA, Jenkins, RE, Jones, DJL, Keevil, B, Krenkel, H, Lane, D, Lane, CS, Lellman, S, Liggett, EN, Meng, X, Mills, C, Mills, K, Nalbant, AA, Ng, LL, Nicholas, B, Noels, D, Pearson, TW, Pitt, A, Pope, ME, Porter, A, Preston, GW, Razavi, M, Shapanis, A, Sidgwick, FR, Singh, R, Skipp, P, Speiss, R, Spiewak, J, Tierney, AL, Trivedi, D, Trost, M, Unwin, RD, Wainwright, L, Walton-Doyle, C, Whetton, AD, Wilks, S & Yip, R 2024 'Development and translation of a method of clinical utility for LC-MS/MS analysis to detect SARS-CoV-2 antigens from ONP swabs and saliva' ChemRxiv. https://doi.org/10.26434/chemrxiv-2024-4t52c

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AU - Anderson, N Leigh

AU - Bailey, Alistair

AU - Barran, Perdita

AU - Brownbridge, Philip

AU - Cain, Kathleen

AU - Carling, Rachel

AU - Cramer, Rainer

AU - Dalton, R Neil

AU - Daly, Matthew E

AU - Davis, Kayleigh

AU - Doykov, Ivan

AU - Dueñas, Maria Emilia

AU - Emmott, Edward

AU - Eyers, Claire E

AU - Gajbhiye, Akshada

AU - Geary, Bethany

AU - Gupta, Pankaj

AU - Hällqvist, Jenny

AU - Hartmane, Evita

AU - Heales, Simon

AU - Heunis, Tiaan

AU - Heywood, Wendy

AU - Hollywood, Katherine A

AU - Jenkins, Rosalind E

AU - Jones, Donald JL

AU - Keevil, Brian

AU - Krenkel, Henriette

AU - Lane, Dan

AU - Lane, Catherine S

AU - Lellman, Sophie

AU - Liggett, Ellen N

AU - Meng, Xiaoli

AU - Mills, Clare

AU - Mills, Kevin

AU - Nalbant, Atakan A

AU - Ng, Leong L

AU - Nicholas, Benjamin

AU - Noels, Dan

AU - Pearson, Terry W

AU - Pitt, Andrew

AU - Pope, Matthew E

AU - Porter, Andrew

AU - Preston, George W

AU - Razavi, Morteza

AU - Shapanis, Andrew

AU - Sidgwick, Frances R

AU - Singh, Raj

AU - Skipp, Paul

AU - Speiss, Reynard

AU - Spiewak, Justyna

AU - Tierney, Anna L

AU - Trivedi, Drupad

AU - Trost, Matthias

AU - Unwin, Richard D

AU - Wainwright, Luke

AU - Walton-Doyle, Caitlin

AU - Whetton, Anthony D

AU - Wilks, Sandra

AU - Yip, Richard

PY - 2024/9/2

Y1 - 2024/9/2

KW - LC-MS

KW - SARS-CoV-2

KW - diagnosis

KW - clinical

KW - proteomics

U2 - 10.26434/chemrxiv-2024-4t52c

DO - 10.26434/chemrxiv-2024-4t52c

M3 - Working paper

BT - Development and translation of a method of clinical utility for LC-MS/MS analysis to detect SARS-CoV-2 antigens from ONP swabs and saliva

PB - ChemRxiv

ER -