Investigating the effects of chelating agents, surfactants and magnesium cations on the size of LPS aggregates in formulations causing low endotoxin recovery in limulus amebocyte lysate assays

Amy Gorman; Mark Becker; Clair Baldock; Stephanie Moore; Alexander P. Golovanov

doi:10.1016/j.ejpb.2025.114861

Investigating the effects of chelating agents, surfactants and magnesium cations on the size of LPS aggregates in formulations causing low endotoxin recovery in limulus amebocyte lysate assays

Amy Gorman, Mark Becker, Clair Baldock, Stephanie Moore, Alexander P. Golovanov

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	European Journal of Pharmaceutics and Biopharmaceutics
DOIs	https://doi.org/10.1016/j.ejpb.2025.114861
Publication status	Published - Nov 2025

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10.1016/j.ejpb.2025.114861Licence: CC BY

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title = "Investigating the effects of chelating agents, surfactants and magnesium cations on the size of LPS aggregates in formulations causing low endotoxin recovery in limulus amebocyte lysate assays",

author = "Amy Gorman and Mark Becker and Clair Baldock and Stephanie Moore and Golovanov, \{Alexander P.\}",

year = "2025",

month = nov,

doi = "10.1016/j.ejpb.2025.114861",

language = "English",

journal = "European Journal of Pharmaceutics and Biopharmaceutics",

issn = "0939-6411",

publisher = "Elsevier BV",

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Investigating the effects of chelating agents, surfactants and magnesium cations on the size of LPS aggregates in formulations causing low endotoxin recovery in limulus amebocyte lysate assays. / Gorman, Amy; Becker, Mark; Baldock, Clair et al.
In: European Journal of Pharmaceutics and Biopharmaceutics, 11.2025.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Investigating the effects of chelating agents, surfactants and magnesium cations on the size of LPS aggregates in formulations causing low endotoxin recovery in limulus amebocyte lysate assays

AU - Gorman, Amy

AU - Becker, Mark

AU - Baldock, Clair

AU - Moore, Stephanie

AU - Golovanov, Alexander P.

PY - 2025/11

Y1 - 2025/11

UR - https://doi.org/10.1016/j.ejpb.2025.114861

U2 - 10.1016/j.ejpb.2025.114861

DO - 10.1016/j.ejpb.2025.114861

M3 - Article

SN - 0939-6411

JO - European Journal of Pharmaceutics and Biopharmaceutics

JF - European Journal of Pharmaceutics and Biopharmaceutics

ER -

Investigating the effects of chelating agents, surfactants and magnesium cations on the size of LPS aggregates in formulations causing low endotoxin recovery in limulus amebocyte lysate assays

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