Restoration of collagen and elastic fibre networks following treatment of photoaged skin with Serènesse, a novel over‐the‐counter anti‐ageing product

A K Langton; J C Mcconnell; L F Cotterell; P Halai; T W Griffiths; C E M Griffiths; R E B Watson

doi:10.1111/jdv.17612

Restoration of collagen and elastic fibre networks following treatment of photoaged skin with Serènesse, a novel over‐the‐counter anti‐ageing product

A K Langton, J C Mcconnell, L F Cotterell, P Halai, T W Griffiths, C E M Griffiths, R E B Watson

Research output: Contribution to journal › Letter › peer-review

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Abstract

Chronic sun exposure induces profound changes to the dermal extracellular matrix (ECM) resulting in the loss of fibrillin-rich microfibrils (FRM) [1] and fibrillar collagen [2]. The gold standard topical treatment for photoaged skin is all-trans retinoic acid (tRA) [3]. The ‘Manchester Patch-Test’ (MPT) assay was first developed in 2001 as a short-term, exaggerated-use patch test protocol to test the potential efficacy of topical anti-ageing products [4].

Original language	English
Journal	Journal of the European Academy of Dermatology and Venereology
Early online date	20 Aug 2021
DOIs	https://doi.org/10.1111/jdv.17612
Publication status	E-pub ahead of print - 20 Aug 2021

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(21 08 06) AKL CG Skin JEADVAccepted author manuscript, 502 KB

https://onlinelibrary.wiley.com/doi/10.1111/jdv.17612

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Langton, A. K., Mcconnell, J. C., Cotterell, L. F., Halai, P., Griffiths, T. W., Griffiths, C. E. M., & Watson, R. E. B. (2021). Restoration of collagen and elastic fibre networks following treatment of photoaged skin with Serènesse, a novel over‐the‐counter anti‐ageing product. Journal of the European Academy of Dermatology and Venereology. Advance online publication. https://doi.org/10.1111/jdv.17612

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title = "Restoration of collagen and elastic fibre networks following treatment of photoaged skin with Ser{\`e}nesse, a novel over‐the‐counter anti‐ageing product",

abstract = "Chronic sun exposure induces profound changes to the dermal extracellular matrix (ECM) resulting in the loss of fibrillin-rich microfibrils (FRM) [1] and fibrillar collagen [2]. The gold standard topical treatment for photoaged skin is all-trans retinoic acid (tRA) [3]. The {\textquoteleft}Manchester Patch-Test{\textquoteright} (MPT) assay was first developed in 2001 as a short-term, exaggerated-use patch test protocol to test the potential efficacy of topical anti-ageing products [4].",

author = "Langton, \{A K\} and Mcconnell, \{J C\} and Cotterell, \{L F\} and P Halai and Griffiths, \{T W\} and Griffiths, \{C E M\} and Watson, \{R E B\}",

year = "2021",

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doi = "10.1111/jdv.17612",

language = "English",

journal = "Journal of the European Academy of Dermatology and Venereology",

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T1 - Restoration of collagen and elastic fibre networks following treatment of photoaged skin with Serènesse, a novel over‐the‐counter anti‐ageing product

AU - Langton, A K

AU - Mcconnell, J C

AU - Cotterell, L F

AU - Halai, P

AU - Griffiths, T W

AU - Griffiths, C E M

AU - Watson, R E B

PY - 2021/8/20

Y1 - 2021/8/20

N2 - Chronic sun exposure induces profound changes to the dermal extracellular matrix (ECM) resulting in the loss of fibrillin-rich microfibrils (FRM) [1] and fibrillar collagen [2]. The gold standard topical treatment for photoaged skin is all-trans retinoic acid (tRA) [3]. The ‘Manchester Patch-Test’ (MPT) assay was first developed in 2001 as a short-term, exaggerated-use patch test protocol to test the potential efficacy of topical anti-ageing products [4].

AB - Chronic sun exposure induces profound changes to the dermal extracellular matrix (ECM) resulting in the loss of fibrillin-rich microfibrils (FRM) [1] and fibrillar collagen [2]. The gold standard topical treatment for photoaged skin is all-trans retinoic acid (tRA) [3]. The ‘Manchester Patch-Test’ (MPT) assay was first developed in 2001 as a short-term, exaggerated-use patch test protocol to test the potential efficacy of topical anti-ageing products [4].

U2 - 10.1111/jdv.17612

DO - 10.1111/jdv.17612

M3 - Letter

SN - 0926-9959

JO - Journal of the European Academy of Dermatology and Venereology

JF - Journal of the European Academy of Dermatology and Venereology

ER -

Restoration of collagen and elastic fibre networks following treatment of photoaged skin with Serènesse, a novel over‐the‐counter anti‐ageing product

Abstract

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The Skin Diary's Night Therapy Repair cream featured in the Times Magazine best luxury buys

The Skin Diary's Night Therapy Repair cream featured on ITV's This Morning programme

The Skin Diary acquires CGSkin in mission to shake up skincare space

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