Research output per year
Research output per year
Personal profile
Overview
Alice is a NoWCADD Postdoctoral Researcher with a background in the characterisation, in-vitro and in-vivo evaluation of nanoparticulate systems. Alice’s experience spans across a range of biological models including multicellular spheroids with projects focused on the exploitation of different strategies to promote the intracellular delivery of nanoparticles. She also uses Ellipsometry to study interactions between nanosystems and lipid monolayers and Raman and Infrared spectroscopy to study cell response to nanoparticle treatments.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Beacons, Institutes and Platforms
- Christabel Pankhurst Institute
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
- 5 Article
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Nucleic Acid-Loaded Lipid Nanoparticle Interactions with Model Endosomal Membranes
Spadea, A., Jackman, M., Cui, L., Pereira, S., Lawrence, M. J., Campbell, R. A. & Ashford, M., 6 Jul 2022, In: ACS applied materials & interfaces. 14, 26, p. 30371-30384Research output: Contribution to journal › Article › peer-review
Open AccessFile158 Downloads (Pure) -
Analysis of Fixed and Live Single Cells Using Optical Photothermal Infrared with Concomitant Raman Spectroscopy
Spadea, A., Denbigh, J., Lawrence, M. J., Kansiz, M. & Gardner, P., 2 Mar 2021, In: Analytical Chemistry. 93, 8, p. 3938-3950 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Microfluidic-assisted preparation of RGD-decorated nanoparticles: exploring integrin-facilitated uptake in cancer cell lines
Spadea, A., Lallana-Ozores, E., Rios De La Rosa, J. M., Donno, R., Lawrence, J., Tirelli, N., Ashford, M., Caswell, P., Puri, S. & Lu, Y., 2 Sept 2020, In: Scientific Reports. 10, 14505.Research output: Contribution to journal › Article › peer-review
Open Access -
Binding and internalization in receptor-targeted carriers. The complex role of CD44 in the uptake of hyaluronic acid-based nanoparticles (siRNA delivery)
Rios De La Rosa, J. M., Pingrajai, P., Pelliccia, M., Spadea, A., Lallana-Ozores, E., Gennari, A., Stratford, I., Rocchia, W., Tirella, A. & Tirelli, N., 18 Dec 2019, In: Advanced Healthcare Materials. 8, 24, 1901182.Research output: Contribution to journal › Article › peer-review
Open Access -
Evaluating the Efficiency of Hyaluronic Acid for Tumor Targeting via CD44
Spadea, A., Rios De La Rosa, J. M., Tirella, A., Ashford, M. B., Williams, K. J., Stratford, I. J., Tirelli, N. & Mehibel, M., 23 Apr 2019, In: Molecular Pharmaceutics. 16, 6, p. 2481–2493Research output: Contribution to journal › Article › peer-review
Thesis
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HYALURONIC ACID BASED NANOPARTICLES FOR SPECIFIC TUMOUR TARGETING
Spadea, A. (Author), Stratford, I. (Supervisor), Williams, K. (Supervisor) & Gieling, R. (Supervisor), 1 Aug 2019Student thesis: Phd
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