Research output per year
Research output per year
Personal profile
Overview
Biography
Proton Therapy Physics Clinical Scientist at The Christie NHS Foundation Trust. Honorary Research Associate at The University of Manchester. Topol Digital Health Fellow for Health Education England.
Working on computational radiobiology, translational radiotherapy, and machine learning in healthcare.
Research interests
Computational Radiobiology
Translation Radiotherapy
Machine Learning in Healthcare
My group
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Karen Kirkby |
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Norman Kirkby Research Fellow |
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Michael Taylor Lecturer in Proton Therapy Physics |
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Michael Merchant Lecturer in Proton Therapy Physics |
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Thomas Mee Research Associate |
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Amy Chadwick Research Associate |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, In silico modelling of radiobiological mechanisms in proton beam therapy, The University of Manchester
1 Oct 2017 → 1 Jan 2021
Award Date: 19 Jan 2022
Master in Science, Clinical Science (Medical Physics), University of Liverpool
Award Date: 6 Dec 2017
Master in Science, Medical Radiation Physics, Swansea University
Award Date: 10 Dec 2014
Bachelor of Science, Theoretical Physics, Swansea University
Award Date: 12 Jul 2013
External positions
Clinical Scientist (Proton Therapy), The Christie Hospital NHS Foundation Trust
Areas of expertise
- QC Physics
- Medical physics
- Radiotherapy
- Biological Modelling
- Machine Learning
Research Beacons, Institutes and Platforms
- Cancer
- Manchester Cancer Research Centre
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Collaborations and top research areas from the last five years
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Research output
- 12 Article
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Challenges and opportunities for Real World Evidence in Radiotherapy – A view from the UK: Proceedings of a national workshop
Craddock, M., Dempsey, C., Abdulwahid, D., Baldwin, J. P. C., Banfill, K., Carver, A., Chaturvedi, A., Cheeseman, S., Cowell, G. W., Daly, M., Dekker, A., Dubash, S. R., Duffield, S., Fornacon-Wood, I., Garcia, M. A. C., Goodley, P., Green, H., Holley, R., Ingram, S. & Jones, S. & 12 others, , 7 Oct 2024, (Accepted/In press) In: ESMO Real World Data and Digital Oncology.Research output: Contribution to journal › Article › peer-review
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Modelling Heterogeneous Anomalous Dynamics of Radiation-Induced Double-Strand Breaks in DNA during Non-Homologous End-Joining Pathway
Korabel, N., Warmenhoven, J. W., Henthorn, N. T., Ingram, S., Fedotov, S., Heaven, C. J., Kirkby, K. J., Taylor, M. J. & Merchant, M. J., 8 Jun 2024, In: Entropy. 26, 6, 502.Research output: Contribution to journal › Article › peer-review
Open Access -
Effects of Differing Underlying Assumptions in In Silico Models on Predictions of DNA Damage and Repair
Warmenhoven, J. W., Henthorn, N. T., Mcnamara, A. L., Ingram, S. P., Merchant, M. J., Kirkby, K. J., Schuemann, J., Paganetti, H., Prise, K. M. & Mcmahon, S. J., 28 Nov 2023, In: Radiation Research. 200, 6, p. 509-522Research output: Contribution to journal › Article › peer-review
Open AccessFile55 Downloads (Pure) -
A computational approach to quantifying miscounting of radiation-induced double-strand break immunofluorescent foci
Ingram, S., Warmenhoven, J., Henthorn, N., Chadwick, A., Santina, E., McMahon, S. J., Schuemann, J., Kirkby, N., Mackay, R., Kirkby, K. & Merchant, M., 14 Jun 2022, (Accepted/In press) In: Communications Biology.Research output: Contribution to journal › Article › peer-review
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The suitability of micronuclei as markers of relative biological effect
Heaven, C. J., Wanstall, H. C., Henthorn, N. T., Warmenhoven, J.-W., Ingram, S. P., Chadwick, A. L., Santina, E., Honeychurch, J., Schmidt, C. K., Kirkby, K. J., Kirkby, N. F., Burnet, N. G. & Merchant, M. J., 2 Apr 2022, In: Mutagenesis. 37, 1, p. 3-12 10 p.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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A computational approach to quantifying miscounting of radiation-induced double-strand break immunofluorescent foci
Ingram, S. (Creator), University of Manchester Figshare, 6 May 2022
DOI: 10.48420/14398790, https://figshare.manchester.ac.uk/articles/dataset/A_computational_approach_to_quantifying_miscounting_of_radiation-induced_double-strand_break_immunofluorescent_foci/14398790
Dataset
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Dataset: Hi-C implementation of genome structure for in silico models of radiation-induced DNA damage
Henthorn, N. (Contributor), Ingram, S. (Creator), Kirkby, K. (Contributor), Kirkby, N. (Contributor), Mackay, R. (Contributor), Merchant, M. (Contributor) & Warmenhoven, J. (Contributor), Mendeley Data, 16 Nov 2020
DOI: 10.17632/kzycj3n2mm.1, https://data.mendeley.com/datasets/kzycj3n2mm
Dataset
Thesis
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In silico modelling of radiobiological mechanisms in proton beam therapy
Ingram, S. (Author), Mackay, R. (Supervisor), Kirkby, K. (Supervisor), Merchant, M. (Supervisor) & Kirkby, N. (Supervisor), 1 Aug 2022Student thesis: Phd
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